Histopharmacology of bone

 

Calcitonin and katacalcin assist the functions of osteoblasts. They break down bone and therefore increase calcium concentration in blood. Parathormone assists the function of osteoclasts and help to break down bone thereby increasing blood calcium level.

Androgens and estrogens  increase growth of bones and also hasten closure of epiphysis. Low estrogen as in postmenopausal syndrome may cause osteoporosis just like increase in interleukin -1 and Il-6 together with tumor necrosis factor (TNF) and increased expression of RANK, RANKL (receptor activation of nuclear factor/ligand). Estrogen treatment reverses this.

 

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Electronic School of Medicine
Creator: Oluwole Ogunranti

      

 


Compact bone explanatory video

 

 

 

Introduction
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Histology
Embryology
Gross anatomy
Organ integration
Clinical anatomy

Quiz

Physiology

Biochemistry

Pharmacology

Chemical Pathology
Anatomical Pathology

Imaging

Medicine

Surgery

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